Gilead

Evaluating the Efficacy and Safety of Selonsertib in Subjects with Moderate to Advanced Diabetic Kidney Disease

Phase 2b, Randomized, Double-Blind, Placebo- Controlled, Parallel Group, Multicenter Study

Tricida

Evaluate the Efficacy and Safety of TRC101 In Subjects with Chronic Kidney Disease and Metabolic Acidosis

Phase 3, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study

Ironwood

Evaluate the Safety and Efficacy Of IW-1973 In Patients with Type 2 Diabetes with Albuminuria Treated with Renin-Angiotensin System Inhibitors

Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study

Pharmacosmos A/S

Comparative Safety and Efficacy Trial of Intravenous Iron Isomaltoside (Monofer) And Iron Sucrose in Subjects with Iron Deficiency Anemia and Non-Dialysis-Dependent Chronic Kidney Disease

Phase III, Randomized, Open-Label

Akebia Therapeutics

Evaluating the Efficacy and Safety of Oral Vadadustat for the Maintenance Treatment of Anemia in Subjects with Non-Dialysis-Dependent Chronic Kidney Disease (NDD-CKD) (PRO2TECT-CONVERSION)

Phase 3, Randomized, Open-Label, Active-Controlled Study

Akebia Therapeutics

Evaluating the Efficacy and Safety of Oral Vadadustat for the Maintenance Treatment of Anemia in Subjects with Dialysis-Dependent Chronic Kidney Disease (DD-CKD) (INO2VATE-CONVERSION)

Phase 3, Randomized, Open-Label, Active-Controlled Study

Akebia Therapeutics

Evaluating the Efficacy and Safety of Oral Vadadustat for the Correction of Anemia in Subjects with Non-Dialysis-Dependent Chronic Kidney Disease (NDD-CKD(PRO2TECT-CORRECTION)

Phase 3, Randomized, Open-Label, Active-Controlled Study

GlaxoSmithKline

Dialysis Subjects with Anemia Associated with Chronic Kidney Disease to Evaluate the Safety and Efficacy of Daprodustat Compared to Recombinant Human Erythropoietin, Following A Switch from Erythropoietin-Stimulating Agents

Phase 3 Randomized, Open-Label (Sponsor-Blind), Active-Controlled, Parallel-Group, Multi-Center, Event Driven Study

GlaxoSmithKline

Non-Dialysis Subjects with Anemia Associated with Chronic Kidney Disease to Evaluate the Safety and Efficacy of Daprodustat Compared to Darbepoetin Alfa

Phase 3 Randomized, Open-Label (Sponsor-Blind), Active-Controlled, Parallel-Group, Multi-Center, Event Driven Study

Bayer

Investigate the Efficacy and Safety of Finerenone, In Addition to Standard of Care, On the Progression of Kidney Disease in Subjects with Type 2 Diabetes Mellitus and The Clinical Diagnosis of Diabetic Kidney Disease

Randomized, Double-Blind, Place-Controlled, Parallel-Group, Multicenter, Event-Driven Phase III Study

Bayer

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Event-Driven Phase III Study to Investigate the Efficacy and Safety of Finerenone on the Reduction of Cardiovascular Morbidity and Mortality in Subjects with Type 2 Diabetes Mellitus and The Clinical Diagnosis of Diabetic Kidney Disease in Addition to Standard of Care

3

Astrazeneca

Evaluating the Safety and Efficacy of Roxadustat for the Treatment of Anemia in Chronic Kidney Disease Patients Not on Dialysis

Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study

Ablynx

Evaluate the Safety and Efficacy Of ALX-0061 Administered Subcutaneously in Subjects with Moderate to Severe Active Systemic Lupus Erythematosus

Phase 2, Multicenter, Randomized, Double-Blind, Placebo Controlled, Dose-Range Finding Study

Takeda

Evaluate the Efficacy and Safety of Febuxostat 40mg XR, 80mg XR, 40mg IR and 80mg IR In Subjects with Gout

Phase 3, Randomized, Double-Blind, Multicenter, Placebo Controlled Study

Pfizer

Evaluate the Efficacy and Safety of Once-Daily Administration of a Chemokine CCR2/5 Receptor Antagonist PF-04634817In Adults with Type 2 Diabetes and Overt Nephropathy

Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multi-Center Study

Amgen

START-CKD: Strategies Using Darbepoetin Alfa To Avoid Transfusions in Chronic Kidney Disease

N/A

Mallinckrodt

Safety and Efficacy Study Of H.P Acthar® Gel (Acthar) In Patients with Diabetic Nephropathy and Proteinuria

Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Adaptive Design Pilot

GlaxoSmithKline

Evaluate the Efficacy and Safety of Belimumab Plus Standard of Care Versus Placebo Plus Standard of Care in Adult Subjects with Active Lupus Nephritis

Phase 3, Randomized, Double-Blind, Placebo-Controlled Study

Reata Pharmaceuticals, Inc.

Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes: The Occurrence of Renal Events, (BEACON)

N/A

Amgen

Trial to Reduce Cardiovascular Events with Aranesp Therapy (TREAT)

N/A

Hoffmann-La Roche

Assess the Efficacy and Safety of Mycophenolate Mofetil (MMF) In Inducing Response and Maintaining Remission in Subjects with Lupus Nephritis

Prospective, Randomized, Active Controlled, Parallel Group, Multi-Center Trial

Abbott

Evaluate the Survival Benefits of Zemplar Relative to Calcijex in Subjects with Stage V Chronic Kidney Disease on Hemodialysis

Phase 4, Prospective, Randomized, Active-Controlled, Double-Blind, Double-Dummy, Multi-Center Study

Pfizer

Linezolid vs. Vancomycin/Cefazolin in The Treatment of Hemodialysis Patients with Catheter Related Gram-Positive Bloodstream Infections

N/A